Cytometry and Imaging

Microscopy - Activities

• Theoretical classes and practical training in photonic microscopy technics   
• Confocal and multiphoton imaging of cells and tissues
• TIRF, live-SR, FRAP, FRET, Photoconversion, Optogenetics
• Multidimensional dynamic imaging in living organs & 3D organoid models
• Support for the development of new optical devices
• Design of experimental procedures
• Scientific animations
• Technological developments and innovation
• Imaging of organoid models
• Development of tools for screening of organoid models.
• Imaging of PDX* mouse models in vivo:
  • Adaptation of the optical chambers developed by the laboratory for long-term and high-resolution dynamic microscopy, on a PDX mouse model.
  • Improvement of stabilization supports for optical chambers, making it possible to avoid the recalibration of images during in vivo kinetic studies
  • Methodological developments for high-resolution imaging of new in vivo models (PDX and CAM - Chicken embryos): adaptation macroscopic, multiphoton and small animal imaging
  (*PDX=patient-derived xenograft models)