La recherche

Major publications

Toppaldoddi KR, da Costa Cacemiro M, Bluteau O, Panneau-Schmaltz B, Pioch A, Muller D, Villeval JL, Raslova H, Constantinescu SN, Plo I, Vainchenker W, Marty C. Rare type 1-like and type 2-like calreticulin mutants induce similar myeloproliferative neoplasms as prevalent type 1 and 2 mutants in mice. Oncogene. 2019 Mar;38(10):1651-1660.

From haematopoietic stem cell to megakaryocyte - current research

back to job offer list

back to clinical trials

From haematopoietic stem cell to megakaryocyte

This group belongs to the UMR 1287: Hematopoietic stem cells and the development of hematological malignancies

Our research:

Bioinformatics platform - Lab members

back to job offer list

back to clinical trials

Bioinformatics core facility - Lab members

Head of the bioinformatics core facility: Marc Deloger (marc.deloger@gustaveroussy.fr)
"Core Service" bioinformaticians (permanent employees): Thibault Dayris, M’boyba Diop, Bastien Job, Gérôme Jules-Clement, Franck Le-Layo.
"Core Service" bioinformaticians (non-permanent employees) : Marine Aglave, Edi Tihic

Bioinformatics platform - Activities

back to job offer list

back to clinical trials

Bioinformatics core facility - Activities

Analysis of (epi)genomic / transcriptomic sequencing data (WGS / WES / TGS, RNA-seq, ChIP / ATAC-seq, Single-Cell, Long Reads)
Data management (recovery, centralization, organization, labeling, provision / sharing)
Support to bioinformaticians, biologists, and clinicians from Gustave Roussy
Publication assistance (material and methods, figures, deposit of data on public databases such as GEO / SRA / EGA / dbGAP)
Co-supervision of junior bioinformaticians (trainees, PhD students…)

Laboratory for Immunomonitoring in Oncology - lab members

back to job offer list

back to clinical trials

Lab members

Lab head
Prof. Nathalie Chaput-Gras
Email

Lab manager
Dr Lydie Cassard

Assistant professor
Dr Marie Naigeon

Engineer
Jean Jouniaux:

Engineer
Lisa Boselli

Technician
Jonathan Grivel:

Laboratory for Immunomonitoring in Oncology (L.I.O) - Equipments

back to job offer list

back to clinical trials

Equipments

1 MACSQuant 16 Cytometer – Miltenyi Biotec Inc.
1 CytoFLEX S base Cytometer – Beckman Coulter
2 GALLIOS Cytometer – Beckman Coulter
MAGPIX Multiplexing System – Luminex B.V.
MESO QuickPlex SQ 120 – Meso Scale Discovery (LRTI)
GentleMACS Dissociator - Miltenyi Biotec Inc.
Vi-CELL XR Cell Analyzer – Beckman Coulter
xCELLigence RTCA - Agilent

Laboratory for Immunomonitoring in Oncology (L.I.O) - Activities

back to job offer list

back to clinical trials

Activities

The Laboratory of Immunomonitoring in Oncology (LIO), created at the end of 2014, is a translational research unit. The main objective of the laboratory is to identify blood or tumor biomarkers that can predict the response or resistance to anti-tumor immunotherapies, as well as the emergence of some immunological adverse effects that may be linked to these treatments. Another objective is to understand the mechanisms of action of anti-tumor immunotherapies.