Développement et fonctions des cellules myéloïdes

Développement et fonctions des cellules myéloïdes : publications majeures

• Kirschenbaum D, Xie K, Ingelfinger F, […], GINHOUX F, Rezvani K, Theis FJ, Yosef N, Weiss T, Weiner A, Amit I. Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma. Cell. 2024 Jan 4;187(1):149-165.e23. doi: 10.1016/j.cell.2023.11.032.  
• Li Z, Pai R, Gupta S, […], GINHOUX F, Sharma A. Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy. Nat Cancer. 2024 Jan;5(1):167186. doi: 10.1038/s43018-023-00672-2.
• Lawrence AR, Canzi A, Bridlance C, […], GINHOUX F, Thion MS, Lokmane L, Garel S. Microglia maintain structural integrity during fetal brain morphogenesis. Cell. 2024 Jan 31:S0092-8674(24)00044-8. doi: 10.1016/j.cell.2024.01.012.
• Park DS, Kozaki T, Tiwari S, […], Cexus O and GINHOUX F. iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation. Nature. 2023 Nov;623(7986):397405. doi: 10.1038/s41586-023-06713-1.
• Park MD, Silvin A, GINHOUX F, Merad M. Macrophages in health and disease. Cell. 2022 Nov 10;185(23):4259-4279. doi: 10.1016/j.cell.2022.10.007.
• Silvin A, Uderhardt S, Piot C, […],  Cexus O, Chen J, Garel S, Dutertre CA, Amit I, Kipnis J, GINHOUX F. Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration. Immunity. 2022 Aug 9;55(8):1448-1465.e6. doi: 10.1016/j.immuni.2022.07.004.
• Mulder K, Patel AA, Kong WT, […], GINHOUX F. Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease. Immunity. 2021 Aug 10;54(8):1883-1900.e5. doi: 10.1016/j.immuni.2021.07.007.  
• Blériot C, Chakarov S, GINHOUX F. Determinants of Resident Tissue Macrophage Identity and Function. Immunity. 2020 Jun 16;52(6):957-970. doi: 10.1016/j.immuni.2020.05.014.
• Takata K, Kozaki T, Lee CZW, […], Pouladi MA and GINHOUX F. Induced-Pluripotent-Stem-CellDerived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function. Immunity. 2017 Jul 18;47(1).